Human entrepreneurship + AI for hard-to-treat disease + military logistics

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December 1, 2025
Greetings! Here’s the latest from the MIT community.
 
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A Passion for Problems
Fellows at the MIT Kuo Sharper Center for Prosperity and Entrepreneurship dream big while staying true to themselves. “MIT taught me the human side of entrepreneurship,” says Arjav Shah SM ’22, PhD ’25, whose startup focuses on therapeutic biologics.
Top Headlines
New AI model could create molecules addressing hard-to-treat diseases
BoltzGen generates protein binders for any biological target from scratch, expanding AI’s reach from understanding biology toward engineering it. 
MIT Heat Island
Why climate and energy entrepreneurs need their own playbook
Climate ventures are capital-intensive, take years to scale, and face unique hurdles. MIT experts explain why these businesses need their own framework.
MIT Heat Island
The unsung role of logistics in the US military
MIT Supply Chain Management hosts Military Fellows each year from the US Army, reflecting the long-standing relationship between the military and the logistics industry. 
MIT Heat Island
#ThisisMIT
In the Media
Opinion: Caregiving is the crack In America’s retirement and longevity planning // Forbes
AgeLab Director Joseph Coughlin underscores how, in his view, “caregiving is the great crack in America’s retirement and longevity plans. While financial security in retirement is, with good reason, often cited as a public crisis, caregiving remains largely a private problem that is only described as an issue.” 
Happenings
A selection of this week’s community events: 
Monday, Dec. 1, 12 p.m. | Center for International Studies presents COP30 Debriefing: A Decade After Paris – What’s Next for Global Climate Action?
Wednesday, Dec. 3, 9:30-11 a.m. | Women’s League presents Coffee Social and Holiday Wreath Making
Wednesday, Dec. 3, 12:10 p.m. | Office of Religious, Spiritual, and Ethical Life presents Christine Southworth: Snowflake Sonifications 
Wednesday, Dec. 3, 4-5:30 p.m. | Office of the President presents Winterfest 2025
Friday, Dec. 5, 4-6 p.m. | Open Space Programming presents Crafternoon: Cozy Cards and Book Swap
Friday, Dec. 5, 8 p.m. | MIT Music and Theater Arts presents 11th Annual PRISM Concert Spectacular
This edition of the MIT Daily was brought to you by a visit to the ballet. ðŸ©°

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